ToTOL Publications since 2013 (65 as of September 2023)

Evaluation of 2-deoxy-2[18F]fluoro glucaric acid (FGA) as a potential PET tracer for tumor necrosis.

Li J, Zheng H, Vega AA, Beverly LJ, Gray BD, Pak KY, Ng CK

Applied Radiation and Isotopes. 2023 August 22. Online first.

UBQLN Family members regulate MYC in Lung Adenocarcinoma cells.

Shah PP and Beverly LJ^.

Cancers.  2023 June 28;15(13):3389. PMID:37444499 PC10340487

Physical structure of constitutional isomers influences antiproliferation activity of thiosemicarbazone-alkylthiocarbamate copper complexes

Bajaj K, Andres SA, Hofsommer DT, Greene AF, Hietsoi O, Mashuta MS, Weis T, Beverly LJ, Bates PJ, Buchanan RM, Grapperhaus CA

J Inorg Biochem.  Online June 7 2023. PMID:3732089

Methionine-producing Tumor Micro(be) Environment fuels Growth of Solid Tumors.

Vega AA, Marshall EA, Noonan AJC, Filho FSL, Yang J, Stewart GL, Johnson FD, Vucic EA, Pewarchuk ME, Shah PP, Clem BF, Nislow C, Lam S, Lockwood WW, Hallam SJ, Leung JM, Beverly LJ^, Lam WL^.

Cellular Oncology. 2023 June15. PMID:37318751

Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS

Kulawala Z, McMillan JD, Singhal RA, Morehouse J, Burke DA, Sears SM, Duregon E, Beverly LJ, Siskind LJ, Friedland RP.

Sci Rep. 2023 Apr 12;13(1):5945.  PMID: 37045868 PMC10097672

Inducing trained immunity in pro-metastatic macrophages to control tumor metastasis.

Ding C, Shrestha R, Zhu X, Geller AE, Wu S, Woeste MR, Li W, Wang H, Yuan F, Xu R, Chariker JH, Hu X, Li H, Tieri D, Zhang HG, Rouchka EC, Mitchell R, Siskind LJ, Zhang X, Xu XG, McMasters KM, Yu Y, Yan J

J.Nat Immunol. 2023 Feb;24(2):239-254. doi: 10.1038/s41590-022-01388-8. Epub 2023 Jan 5. PMID: 36604547

Lung cancer-kidney cross talk induces kidney injury, interstitial fibrosis and enhances cisplatin-induced nephrotoxicity

Orwick A, Sears SM, Sharp CN, Doll MA, Shah PP, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2023 March 1;324(3):F287-300. PMID: 36727944 PMC9988526

Pharmacological inhibitors of autophagy have opposite effects in acute and chronic cisplatin-induced kidney injury

Sears SM, Feng JL, Orwick A, Vega AA, Krueger AM, Shah PP, Doll MA, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2022 Sep; 323(3):F288-F298.  PMID: 35796459 PMC9394729

F4/80hi resident macrophages contribute to cisplatin-induced renal fibrosis.

Sears SM, Vega AA, Kurlawala Z, Oropilla GB, Krueger A, Shah PP, Doll MA, Miller R, Beverly LJ and Siskind LJ.

Kidney360 May 2022, 3(5)818-833.

Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury

Sears SM, Dupre TV, Shah PP, Davis DL, Doll MA, Sharp CN, Vega AA, Megyesi J, Beverly LJ, Snider AJ, Obeid LM, Hannun YA and Siskind LJ.

J Lipid Res. 2022 March;63(3):100179. PMCID: PMC8953688 PMID: 35151662

Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

Bushau-Sprinkle AM, Barati MT, Xheng Y, Watson WH, Gagnon KB, Khundmiri SJ, Kitterman KT, Clark BJ, Siskind LJ, Doll MA, Brier ME, Conventry S and Lederer ED.

Antioxidants (Basel) 2021 Jun 28;10(7):1036

Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis

Doll MA, Ray AR, Salazar-Gonzalez RA, Shah PP, Vega AA, Sears SM, Krueger AM, Hong KU, Beverly LJ and Hein DW

Molecular Carcinogenesis. 2022 May;61(5):481-493. PMID:35133049

Towards a molecular understanding of the overlapping and distinct roles of UBQLN1 and UBQLN2 in lung cancer progression and metastasis

Shah PP, Saurabh K, Vega AA, Siskind LJ and Beverly LJ

Neoplasia. Accepted for publication Nov. 2021

Potential Therapeutic Targets for Cisplatin-Induced Kidney Injury: Lessons from Other Models of AKI and Fibrosis.

Sears S, Siskind L.

J Am Soc Nephrol. 2021 May 28:ASN.2020101455. doi: 10.1681/ASN.2020101455. Online ahead of print.PMID: 34049962

Progression of Nonmotor Symptoms in Parkinson's Disease by Sex and Motor Laterality.

Kurlawala Z, Shadowen PH, McMillan JD, Beverly LJ, Friedland RP.

Parkinsons Dis. 2021 Apr 1;2021:8898887. doi: 10.1155/2021/8898887. eCollection 2021.PMID: 33868631

Neutral Ceramidase Mediates Nonalcoholic Steatohepatitis by Regulating Monounsaturated Fatty Acids and Gut IgA+ B Cells.

Gu X, Sun R, Chen L, Chu S, Doll MA, Li X, Feng W, Siskind L, McClain CJ, Deng Z.

Hepatology. 2021 Mar;73(3):901-919. doi: 10.1002/hep.31628. Epub 2021 Feb 18.PMID: 33185911

NHERF1 Loss Upregulates Enzymes of the Pentose Phosphate Pathway in Kidney Cortex

Bushau-Sprinkle A, Barati MT, Gagnon KB, Khundmiri SJ, Kitterman K, Hill BG, Sherwood A, Merchant M, Rai SN, Srivastava S, Clark B, Siskind L, Brier M, Hata J, Lederer E

Antioxidants (Basel). 2020 Sep 14;9(9):862 doi:10.3390/antiox9090862 PMID:32937931

UBR-box containing protein, UBR5, is over-expressed in human lungadenocarcinoma and is a potential therapeutic target.

Saurabh K, Shah PP, Doll MA, Siskind LJ, Beverly LJ.

BMC Cancer. 2020 Aug 31;20(1):824. doi: 10.1186/s12885-020-07322-1. PMID: 32867711 

 C57BL/6 mice require a higher dose of cisplatin to induce renal fibrosis and CCL2 correlates with cisplatin-induced kidney injury.  

Sears SM, Sharp CN, Krueger AM, Oropilla GB, Saforo D, Doll M, Megyesi J, Beverly LJ and Siskind LJ.

Am J Physiol Renal Physiol.  2020 Aug 24. Online ahead of print. PMID: 32830540

Ubiquilin proteins regulate EGFR levels and activity in lung adenocarcinoma cells.

Kurlawala Z, Saurabh K, Dunaway R, Shah PP, Siskind LJ, Beverly LJ.

J Cell Biochem. 2020 Jul 28. doi: 10.1002/jcb.29830. Online ahead of print.

PMID: 32720736

Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia.

Barve A, Vega A, Shah PP, Ghare S, Casson L, Wunderlich M, Siskind LJ, Beverly LJ.

Cells. 2019 Oct 25;8(11):1322. doi: 10.3390/cells8111322.

PMID: 31717699

Computational/experimental evaluation of liver metastasis post hepatic injury: interactions with macrophages and transitional ECM.

Hudson SV, Miller HA, Mahlbacher GE, Saforo D, Beverly LJ, Arteel GE, Frieboes HB.

Sci Rep. 2019 Oct 21;9(1):15077. doi: 10.1038/s41598-019-51249-y.

PMID: 31636296

De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues.

Fan TWM, Bruntz RC, Yang Y, Song H, Chernyavskaya Y, Deng P, Zhang Y, Shah PP, Beverly LJ, Qi Z, Mahan AL, Higashi RM, Dang CV, Lane AN.

J Biol Chem. 2019 Jul 23. pii: jbc.RA119.008743. doi: 10.1074/jbc.RA119.008743. [Epub ahead of print]

PMID: 31337706 

Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.

Khan N, Shah PP, Ban D, Trigo-Mouriño P, Carneiro MG, DeLeeuw L, Dean WL, Trent JO, Beverly LJ, Konrad M, Lee D, Sabo TM.

J Biol Chem. 2019 Aug 2;294(31):11920-11933. doi: 10.1074/jbc.RA119.009251. Epub 2019 Jun 14

PMID: 31201273

Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury.

Bushau-Sprinkle A, Barati M, Conklin C, Dupre T, Gagnon KB, Khundmiri SJ, Clark B, Siskind L, Doll MA, Rane M, Brier M, Coventry S, Lederer ED.

Am J Pathol. 2019 Jun;189(6):1190-1200. doi: 10.1016/j.ajpath.2019.02.010. Epub 2019 Mar 27.

PMID: 30926337

Primary lung cancer samples cultured under microenvironment-mimetic conditions enrich for mesenchymal stem-like cells that promote metastasis.

Saforo D, Omer L, Smolenkov A, Barve A, Casson L, Boyd N, Clark G, Siskind L, Beverly L.

Sci Rep. 2019 Mar 12;9(1):4177. doi: 10.1038/s41598-019-40519-4.

PMID: 30862796 Free PMC Article

Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis.

O'Farrell H, Harbourne B, Kurlawala Z, Inoue Y, Nagelberg AL, Martinez VD, Lu D, Oh MH, Coe BP, Thu KL, Somwar R, Lam S, Lam WL, Unni AM, Beverly L, Lockwood WW.

J Thorac Oncol. 2019 Apr;14(4):656-671. doi: 10.1016/j.jtho.2018.12.004. Epub 2018 Dec 19.

PMID: 30578931

Moderate aging does not exacerbate cisplatin-induced kidney injury or fibrosis despite altered inflammatory cytokine expression and immune cell infiltration.

Sharp CN, Doll M, Dupre TV, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F162-F172. doi: 10.1152/ajprenal.00463.2018. Epub 2018 Nov 28.

PMID: 30484347

The role of sphingolipids in acute kidney injury.

Dupre TV, Siskind LJ.

Adv Biol Regul. 2018 Dec;70:31-39. doi: 10.1016/j.jbior.2018.11.003. Epub 2018 Nov 13. Review.

PMID: 30455062

Comparative utility of NRG and NRGS mice for the study of normal hematopoiesis, leukemogenesis, and therapeutic response.

Barve A, Casson L, Krem M, Wunderlich M, Mulloy JC, Beverly LJ.

Exp Hematol. 2018 Nov;67:18-31. doi: 10.1016/j.exphem.2018.08.004. Epub 2018 Aug 17.

PMID: 30125602

The Antiarrhythmic Drug, Amiodarone, Decreases AKT Activity and Sensitizes Human Acute Myeloid Leukemia Cells to Apoptosis by ABT-263.

Ketchem CJ, Kucera C, Barve A, Beverly LJ.

Am J Med Sci. 2018 May;355(5):488-496. doi: 10.1016/j.amjms.2018.01.011. Epub 2018 Feb 6.

PMID: 29753379 Free Article

Teaching Old Drugs New Tricks: Repositioning Pharmaceuticals for Bench to Bedside Success.

Beverly LJ, Krem MM.

Am J Med Sci. 2018 Mar;355(3):205-206. doi: 10.1016/j.amjms.2017.12.007. Epub 2017 Dec 26. No abstract available.

PMID: 29549920

Subclinical kidney injury induced by repeated cisplatin administration results in progressive chronic kidney disease.

Sharp CN, Doll MA, Megyesi J, Oropilla GB, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2018 Jul 1;315(1):F161-F172. doi: 10.1152/ajprenal.00636.2017. Epub 2018 Jan 31.

PMID: 29384415 Free PMC Article

Neuraminidase activity mediates IL-6 production by activated lupus-prone mesangial cells.

Sundararaj K, Rodgers JI, Marimuthu S, Siskind LJ, Bruner E, Nowling TK.

Am J Physiol Renal Physiol. 2018 Apr 1;314(4):F630-F642. doi: 10.1152/ajprenal.00421.2017. Epub 2017 Dec 20.

PMID: 29357434 Free PMC Article

Regulation of insulin-like growth factor receptors by Ubiquilin1.

Kurlawala Z, Dunaway R, Shah PP, Gosney JA, Siskind LJ, Ceresa BP, Beverly LJ.

Biochem J. 2017 Dec 6;474(24):4105-4118. doi: 10.1042/BCJ20170620.

PMID: 29054976 Free PMC Article

Developing better mouse models to study cisplatin-induced kidney injury.

Sharp CN, Siskind LJ.

Am J Physiol Renal Physiol. 2017 Oct 1;313(4):F835-F841. doi: 10.1152/ajprenal.00285.2017. Epub 2017 Jul 19. Review.

PMID: 28724610 Free PMC Article

Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.

Dupre TV, Doll MA, Shah PP, Sharp CN, Siow D, Megyesi J, Shayman J, Bielawska A, Bielawski J, Beverly LJ, Hernandez-Corbacho M, Clarke CJ, Snider AJ, Schnellmann RG, Obeid LM, Hannun YA, Siskind LJ.

J Lipid Res. 2017 Jul;58(7):1439-1452. doi: 10.1194/jlr.M076745. Epub 2017 May 10.

PMID: 28490444 Free PMC Article

MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis.

Yadav S, Singh N, Shah PP, Rowbotham DA, Malik D, Srivastav A, Shankar J, Lam WL, Lockwood WW, Beverly LJ.

Neoplasia. 2017 Apr;19(4):321-332. doi: 10.1016/j.neo.2017.02.001. Epub 2017 Mar 16.

PMID: 28315615 Free PMC Article

Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress.

Shah PP, Dupre TV, Siskind LJ, Beverly LJ.

Oncotarget. 2017 Apr 4;8(14):22625-22639. doi: 10.18632/oncotarget.15150.

PMID: 28186986 Free PMC Article

The STI and UBA Domains of UBQLN1 Are Critical Determinants of Substrate Interaction and Proteostasis.

Kurlawala Z, Shah PP, Shah C, Beverly LJ.

J Cell Biochem. 2017 Aug;118(8):2261-2270. doi: 10.1002/jcb.25880. Epub 2017 Apr 25.

PMID: 28075048 Free PMC Article

Bridging translation for acute kidney injury with better preclinical modeling of human disease.

Skrypnyk NI, Siskind LJ, Faubel S, de Caestecker MP.

Am J Physiol Renal Physiol. 2016 May 15;310(10):F972-84. doi: 10.1152/ajprenal.00552.2015. Epub 2016 Mar 9. Review.

PMID: 26962107 Free PMC Article

Methods to Study Metastasis in Genetically Modified Mice.

Kabeer F, Beverly LJ, Darrasse-Jèze G, Podsypanina K.

Cold Spring Harb Protoc. 2016 Feb 1;2016(2):pdb.top069948. doi: 10.1101/pdb.top069948.

PMID: 26832689

Murine Stem Cell-Based Retrovirus Production for Marking Primary Mouse Mammary Cells for Metastasis Studies.

Beverly LJ, Podsypanina K.

Cold Spring Harb Protoc. 2016 Feb 1;2016(2):pdb.prot078337. doi: 10.1101/pdb.prot078337.

PMID: 26832680

Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.

Sundaram K, Mather AR, Marimuthu S, Shah PP, Snider AJ, Obeid LM, Hannun YA, Beverly LJ, Siskind LJ.

Biochem J. 2016 Mar 15;473(6):743-55. doi: 10.1042/BJ20150586. Epub 2016 Jan 8.

PMID: 26747710 Free PMC Article

Repeated administration of low-dose cisplatin in mice induces fibrosis.

Sharp CN, Doll MA, Dupre TV, Shah PP, Subathra M, Siow D, Arteel GE, Megyesi J, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2016 Mar 15;310(6):F560-8. doi: 10.1152/ajprenal.00512.2015. Epub 2016 Jan 6.

PMID: 26739893 Free PMC Article

 Suramin protects from cisplatin-induced acute kidney injury.

Dupre TV, Doll MA, Shah PP, Sharp CN, Kiefer A, Scherzer MT, Saurabh K, Saforo D, Siow D, Casson L, Arteel GE, Jenson AB, Megyesi J, Schnellmann RG, Beverly LJ, Siskind LJ.

Am J Physiol Renal Physiol. 2016 Feb 1;310(3):F248-58. doi: 10.1152/ajprenal.00433.2015. Epub 2015 Dec 9.

PMID: 26661653 Free PMC Article

Ceramide channel: Structural basis for selective membrane targeting.

Perera MN, Ganesan V, Siskind LJ, Szulc ZM, Bielawska A, Bittman R, Colombini M.

Chem Phys Lipids. 2016 Jan;194:110-116. doi: 10.1016/j.chemphyslip.2015.09.007. Epub 2015 Sep 25.

PMID: 26408265 Free PMC Article

Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular Properties.

Scherzer MT, Waigel S, Donninger H, Arumugam V, Zacharias W, Clark G, Siskind LJ, Soucy P, Beverly L.

PLoS One. 2015 Sep 15;10(9):e0138065. doi: 10.1371/journal.pone.0138065. eCollection 2015.

PMID: 26371754 Free PMC Article

Ceramide channels: destabilization by Bcl-xL and role in apoptosis.

Chang KT, Anishkin A, Patwardhan GA, Beverly LJ, Siskind LJ, Colombini M.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2374-84. doi: 10.1016/j.bbamem.2015.07.013. Epub 2015 Jul 26.

PMID: 26215742 Free PMC Article

Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells.

Subathra M, Korrapati M, Howell LA, Arthur JM, Shayman JA, Schnellmann RG, Siskind LJ.

Am J Physiol Renal Physiol. 2015 Aug 1;309(3):F204-15. doi: 10.1152/ajprenal.00150.2015. Epub 2015 Jun 3.

PMID: 26041445 Free PMC Article

Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelial-mesenchymal transition (EMT) downstream of ER stress.

Shah PP, Beverly LJ.

Oncotarget. 2015 Jul 10;6(19):17725-37.

PMID: 25970786 Free PMC Article

Sphingolipids and mitochondrial apoptosis.

Patwardhan GA, Beverly LJ, Siskind LJ.

J Bioenerg Biomembr. 2016 Apr;48(2):153-68. doi: 10.1007/s10863-015-9602-3. Review.

PMID: 25620271 Free PMC Article

 Renal glycosphingolipid metabolism is dysfunctional in lupus nephritis.

Nowling TK, Mather AR, Thiyagarajan T, Hernández-Corbacho MJ, Powers TW, Jones EE, Snider AJ, Oates JC, Drake RR, Siskind LJ.

J Am Soc Nephrol. 2015 Jun;26(6):1402-13. doi: 10.1681/ASN.2014050508. Epub 2014 Sep 30.

PMID: 25270066 Free PMC Article

The PIM family of oncoproteins: small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets.

Saurabh K, Scherzer MT, Shah PP, Mims AS, Lockwood WW, Kraft AS, Beverly LJ.

Oncotarget. 2014 Sep 30;5(18):8503-14.

PMID: 25238262 Free PMC Article

Glucose availability and glycolytic metabolism dictate glycosphingolipid levels.

Stathem M, Marimuthu S, O'Neal J, Rathmell JC, Chesney JA, Beverly LJ, Siskind LJ.

J Cell Biochem. 2015 Jan;116(1):67-80. doi: 10.1002/jcb.24943.

PMID: 25145677 Free PMC Article

Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.

Perry DM, Newcomb B, Adada M, Wu BX, Roddy P, Kitatani K, Siskind L, Obeid LM, Hannun YA.

J Biol Chem. 2014 Aug 8;289(32):22401-12. doi: 10.1074/jbc.M114.589648. Epub 2014 Jun 20.

PMID: 24951586 Free PMC Article

IRAK1: oncotarget in MDS and AML.

Beverly LJ, Starczynowski DT.

Oncotarget. 2014 Apr 15;5(7):1699-700. No abstract available.

PMID: 24880611 Free PMC Article

Ubiquilin1 represses migration and epithelial-to-mesenchymal transition of human non-small cell lung cancer cells.

Shah PP, Lockwood WW, Saurabh K, Kurlawala Z, Shannon SP, Waigel S, Zacharias W, Beverly LJ.

Oncogene. 2015 Mar 26;34(13):1709-17. doi: 10.1038/onc.2014.97. Epub 2014 Apr 21.

PMID: 24747970 Free PMC Article

Dissecting the in vivo leukemogenic potency of BCLxl.

Saurabh K, Scherzer MT, Song A, Yip KW, Reed JC, Li C, Beverly LJ.

J Leuk (Los Angel). 2014;2(5):158. Epub 2014 Sep 24.

PMID: 26636115 Free PMC Article

Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism.

Richard EM, Thiyagarajan T, Bunni MA, Basher F, Roddy PO, Siskind LJ, Nietert PJ, Nowling TK.

PLoS One. 2013 Sep 10;8(9):e75175. doi: 10.1371/journal.pone.0075175. eCollection 2013.

PMID: 24040398 Free PMC Article

Suramin: a potential therapy for diabetic nephropathy.

Korrapati MC, Howell LA, Shaner BE, Megyesi JK, Siskind LJ, Schnellmann RG.

PLoS One. 2013 Sep 9;8(9):e73655. doi: 10.1371/journal.pone.0073655. eCollection 2013. Erratum in: PLoS One. 2014;9(1):e114426. Howell, Lauren H [corrected to Howell, Lauren A].

PMID: 24040012 Free PMC Article

Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome.

Rhyasen GW, Bolanos L, Fang J, Jerez A, Wunderlich M, Rigolino C, Mathews L, Ferrer M, Southall N, Guha R, Keller J, Thomas C, Beverly LJ, Cortelezzi A, Oliva EN, Cuzzola M, Maciejewski JP, Mulloy JC, Starczynowski DT.

Cancer Cell. 2013 Jul 8;24(1):90-104. doi: 10.1016/j.ccr.2013.05.006.

PMID: 23845443 Free PMC Article

The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers.

Lockwood WW, Chandel SK, Stewart GL, Erdjument-Bromage H, Beverly LJ.

PLoS One. 2013 May 2;8(5):e63610. doi: 10.1371/journal.pone.0063610. Print 2013.

PMID: 23658844 Free PMC Article

BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins.

Beverly LJ, Howell LA, Hernandez-Corbacho M, Casson L, Chipuk JE, Siskind LJ.

Biochem J. 2013 May 15;452(1):111-9. doi: 10.1042/BJ20130147.

PMID: 23480852 Free PMC Article

Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteins.

Casson L, Howell L, Mathews LA, Ferrer M, Southall N, Guha R, Keller JM, Thomas C, Siskind LJ, Beverly LJ.

PLoS One. 2013;8(1):e54525. doi: 10.1371/journal.pone.0054525. Epub 2013 Jan 16.

PMID: 23342165 Free PMC Article